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Get Molecular Testing - Ontario

As of July 1st, 2024, Ontario patients living with cholangiocarcinoma will be able to access molecular testing from UHN’s Laboratory Medicine Program (UHN-LMP), in partnership with the C3. UHN-LMP uses a “Custom Solid Tumour (CST) v1 Panel”, which can detect FGFR2 fusions and additional DNA/RNA biomarkers (see below for full list).

 

Patients and treating physician will receive a complete clinical report indicating Tier I (variants of strong clinical significance) and Tier II (variants of potential clinical significance) alterations in DNA and RNA biomarkers.

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To be eligible for C3 funded testing, the patient must be a member of the C3 and physicians must submit a C3 Patient Attestation form and UHN-LMP Test Requisition Form.

Important Information:

  • Patients must be a "C3 Patient Member" 

    • Please fill out the C3 Attestation form and refer your patients to fill out the C3 Intake form

  • On Page 1 of the UHN-C3 Test Requisition Form​,    you will find information on Sample Requirements

  • On Page 2 of the UHN-C3 Test Requisition Form, under "Cholangiocarcinoma", please check  the "Canadian Cholangiocarcinoma Collaborative (C3)" option and continue to complete all forms

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  • Please notify the C3 about test orders by filling out the C3 notification form  

  • All completed forms (Test Requisition and C3 Attestations) should be sent with the specimen to:

    • Toronto General Hospital​
      Eaton Wing 11-444, 200 Elizabeth Street
      Toronto, Ontario, M5G 2C4
      Attn: Dr. Shamini Selvarajah

    • Please do not fax or email these forms in advance, but if you have questions about ordering please contact us

Forms for UHN-LMP x C3

Contact and Assistance Information:

Answers to FAQ

  • The patient will get a clinical grade NGS report including FGFR fusions and additional relevant BTC targets 

    • note: CCO funded testing reports only FGFR

    • See bottom of page for all targets

  • Patients need to register with C3 by contacting  c3@ohri.ca or providing permission for the C3 to contact them

  • Patients do not have to be seen at UHN in order to receive testing

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*UHN-LMP provides Clinical-Grade Molecular Testing (CAP# 7175217/CLIA# 99D1106115)

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